Modelling structure-function relationships in the utero-placental vasculature
Several physiological changes happen dynamically over the course of a pregnancy. One of the most important, and dramatic of these changes is the development of the utero-placental vasculature, which comprises two blood circulations with mum’s blood feeding baby and supplying nutrient rich blood via the uterus, and baby exchanging nutrients and waste with mum’s circulation via the placenta. Here I will tell the story of how the utero-placental circulation evolves in early pregnancy to ensure a good supply of nutrients to the fetus, and will discuss how mathematical modelling approaches can contribute to understanding the physiology of the system across multiple spatial and temporal scales.
Dr Alys Clark, University of Auckland