Genelle F Harrison, Laura Ann Leaton, Marte K Viken, Jonathan Shortt, Christopher R Gignoux, Benedicte A Lie, D. Vukcevic, S. Leslie, Paul J Norman. Allele imputation for the Killer cell Immunoglobulin-like Receptor KIR3DL1/S1. 2021. doi: 10.1101/2021.05.13.443975.
Frauke Degenhardt, Gabriele Mayr, Mareike Wendorff, Gabrielle Boucher, Eva Ellinghaus, Hesham ElAbd, Elisa Rosati, Matthias Hübenthal, Simonas Juzenas, Shifteh Abedian, Homayon Vahedi, BK Thelma, Suk-Kyun Yang, Byong Duk Ye, Jae Hee Cheon, Lisa Wu Datta, Naser Ebrahim Daryani, Pierre Ellul, Motohiro Esaki, Yuta Fuyuno, Dermot PB McGovern, Talin Haritunians, Myhunghee Hong, Garima Juyal, Eun Suk Jung, Michiaki Kubo, Subra Kugathasan, Tobias L Lenz, S. Leslie, Reza Malekzadeh, Vandana Midha, A. Motyer, David T Okou, Soumya Raychaudhuri, John Schembri, Stefan Schreiber, Kyuyoung Song, Ajit Sood, Atsushi Takahashi, Esther A Torres, Junji Umeno, Behrooz Z Alizadeh, Rinse K Weersma, Sunny H Wong, Keiko Yamazaki, Tom H Karlsen, John D Rioux, Steven R Brant, MAAIS Recruitment Center, Andre Franke, International IBD Genetics Consortium, S Hwong, for the MAAIS Recruitment Center, for the International IBD Genetics Consortium. Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations.. Human molecular genetics, 30, 356-369, 2021. doi: 10.1093/hmg/ddab017.
Simon Easteal, Ruth M Arkell, Renzo F Balboa, Shayne A Bellingham, Alex D Brown, Tom Calma, Matthew C Cook, Megan Davis, Hugh JS Dawkins, Marcel E Dinger, Michael S Dobbie, A. Farlow, Kylie G Gwynne, Azure Hermes, Wendy E Hoy, Misty R Jenkins, Simon H Jiang, Warren Kaplan, S. Leslie, Bastien Llamas, Graham J Mann, Brendan J McMorran, Rebekah E McWhirter, Cliff J Meldrum, Shivashankar H Nagaraj, Saul J Newman, Jack S Nunn, Lyndon Ormond-Parker, Neil J Orr, Devashi Paliwal, Hardip R Patel, Glenn Pearson, Greg R Pratt, Boe Rambaldini, Lynette W Russell, Ravi Savarirayan, Matthew Silcocks, John C Skinner, Yassine Souilmi, Carola G Vinuesa, Gareth Baynam. Equitable Expanded Carrier Screening Needs Indigenous Clinical and Population Genomic Data. The American Journal of Human Genetics, 107, 175-182, 2020. doi: 10.1016/j.ajhg.2020.06.005.
Aimee L Hanson, International Genetics of Ankylosing Spondylitis Consortium, D. Vukcevic, S. Leslie, Jessica Harris, Kim-Anh Lê Cao, Tony J Kenna, Matthew A Brown. Epistatic interactions between killer immunoglobulin-like receptors and human leukocyte antigen ligands are associated with ankylosing spondylitis.. PLoS Genet, 16, e1008906 (26pp), 2020. doi: 10.1371/journal.pgen.1008906.
G. Tsambos, Peter Ralph, Jerome Kelleher, S. Leslie, D. Vukcevic. Efficient simulation of ancestry in large datasets. GENETIC EPIDEMIOLOGY, 44, 524 (1pp), 2020.
JP Rubio, A. Motyer, S Jackson, DA Markalanda, I Harliwong, C Ye, A Shiu, T Tian, JL Fink, A Harding, M Barnett, S. Leslie. Using single cell DNA-seq to decipher disease mechanisms for MS. MULTIPLE SCLEROSIS JOURNAL, 26, NP21-NP22, 2020.
David McG Squire, A. Motyer, Richard Ahn, Joanne Nititham, Z. HUANG, Jorge R Oksenberg, John Foerster, Wilson Liao, S. Leslie. MHC*IMP – Imputation of Alleles for Genes in the Major Histocompatibility Complex. 2020.01.24.919191, 2020. doi: 10.1101/2020.01.24.919191.
Rebecca L Yanovsky, Haoyan Chen, S. Leslie, Mary Carrington, Wilson Liao. The Interaction of LILRB2 with HLA-B Is Associated with Psoriasis Susceptibility.. The Journal of investigative dermatology, 1292-+, 2019. doi: 10.1016/j.jid.2019.12.006.
Paul A Lyons, James E Peters, Federico Alberici, James Liley, Richard MR Coulson, William Astle, Chiara Baldini, Francesco Bonatti, Maria C Cid, Heather Elding, Giacomo Emmi, Joerg Epplen, Loic Guillevin, David RW Jayne, Tao Jiang, Iva Gunnarsson, Peter Lamprecht, S. Leslie, Mark A Little, Davide Martorana, Frank Moosig, Thomas Neumann, Sophie Ohlsson, Stefanie Quickert, Giuseppe A Ramirez, Barbara Rewerska, Georg Schett, Renato A Sinico, Wojciech Szczeklik, Vladimir Tesar, D. Vukcevic, Mohammed Akil, Jonathan Barratt, Neil Basu, Adam S Butterworth, Ian Bruce, Michael Clarkson, Niall Conlon, Bhaskar DasGupta, Timothy WR Doulton, Georgina Espigol-Frigole, Oliver Flossmann, Armando Gabrielli, Jolanta Gasior, Gina Gregorini, Giuseppe Guida, Jose Hernandez-Rodriguez, Zdenka Hruskova, Amy Hudson, Ann Knight, Peter Lanyon, Raashid Luqmani, Malgorzata Magliano, Angelo A Manfredi, Christopher Marguerie, Federica Maritati, Chiara Marvisi, Neil J McHugh, Eamonn Molloy, A. Motyer, Chetan Mukhtyar, Leonid Padyukov, Alber. Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status.. Nature communications, 10, 5120 (13pp), 2019. doi: 10.1038/s41467-019-12515-9.
Limy Wong, Federica Mescia, Federico Alberici, Miriam J Ball, Bo Baslund, Paul Brenchley, Annette Bruchfeld, Maria C Cid, Jan Willem Cohen Tervaert, Richard MR Coulson, Neda Farahi, Conleth Feighery, Wolfgang L Gross, Loic Guillevin, Iva Gunnarsson, Lorraine Harper, Julia U Holle, Zdenka Hruskova, David RW Jayne, Peter Lamprecht, S. Leslie, Mark A Little, Davide Martorana, Thomas Neumann, Sophie Ohlsson, Chen Au Peh, Charles D Pusey, Stefanie Quickert, Giuseppe A Ramirez, Andrew J Rees, Barbara Rewerska, Alan D Salama, Jan-Stephan F Sanders, Caroline O Savage, Marten Segelmark, Roser Solans, Coen A Stegeman, Wojciech Szczeklik, Benjamin Terrier, Vladimir Tesar, Richard A Watts, Stefan Wieczorek, Benjamin Wilde, Jochen Zwerina, Augusto Vaglio, Paul A Lyons, Kenneth GC Smith. GENETIC EVIDENCE OF EOSINOPHIL NUMBER UNDERPINNING PR3-AAV AND PLAUSIBLE HOST GENETIC PREDISPOSITION TO MICROBIAL DRIVERS OF DISEASE. RHEUMATOLOGY, 58, 80-81, 2019.
Rebecca L Yanovsky, Haoyan Chen, S. Leslie, Mary Carrington, Wilson Liao. The Interaction of LILRB2 with HLA-B is Associated with Psoriasis Susceptibility. 2019. doi: 10.1101/741983.
Limy Wong, Federica Mescia, Federico Alberici, Miriam J Ball, Bo Baslund, Paul Brenchley, Annette Bruchfeld, Maria C Cid, Jan Willem Cohen Tervaert, Richard MR Coulson, Neda Farahi, Conleth Feighery, Wolfgang L Gross, Loic Guillevin, Iva Gunnarsson, Lorraine Harper, Julia U Holle, Zdenka Hruskova, David RW Jayne, Peter Lamprecht, S. Leslie, Mark A Little, Davide Martorana, Thomas Neumann, Sophie Ohlsson, Chen Au Peh, Charles D Pusey, Stefanie Quickert, Giuseppe A Ramirez, Andrew J Rees, Barbara Rewerska, Alan D Salama, Jan-Stephan F Sanders, Caroline O Savage, Marten Segelmark, Roser Solans, Coen A Stegeman, Wojciech Szczeklik, Benjamin Terrier, Vladimir Tesar, Richard A Watts, Stefan Wieczorek, Benjamin Wilde, Jochen Zwerina, Augusto Vaglio, Paul A Lyons, Kenneth GC Smith. 185.?Genetic evidence of eosinophil number underpinning PR3-AAV and plausible host genetic predisposition to microbial drivers of disease. Rheumatology, 58, 2019. doi: 10.1093/rheumatology/kez060.012.
FC Garton, PJ Houweling, D. Vukcevic, LR Meehan, FXZ Lee, M Lek, KN Roeszler, MW Hogarth, CF Tiong, D. Zannino, N Yang, S. Leslie, P Gregorevic, SI Head, JT Seto, KN North. The Effect of ACTN3 Gene Doping on Skeletal Muscle Performance. American Journal of Human Genetics, 845-857, 2018. doi: 10.1016/j.ajhg.2018.03.009.
DJ Pappas, A Lizee, V Paunic, KR Beutner, A. Motyer, D. Vukcevic, S. Leslie, J Biesiada, J Meller, KD Taylor, X Zheng, LP Zhao, P-A Gourraud, JA Hollenbach, SJ Mack, M Maiers. Significant variation between SNP-based HLA imputations in diverse populations: the last mile is the hardest. PHARMACOGENOMICS JOURNAL, 18, 367-376, 2018. doi: 10.1038/tpj.2O17.7.
Clare Bycroft, Colin Freeman, Desislava Petkova, Gavin Band, Lloyd T Elliott, Kevin Sharp, A. Motyer, D. Vukcevic, Olivier Delaneau, Adrian Cortes, Samantha Welsh, Alan Young, Mark Effingham, Gil McVean, S. Leslie, Naomi Allen, Peter Donnelly, Jonathan Marchini, J O Connell. The UK Biobank resource with deep phenotyping and genomic data.. Nature, 562, 203-+, 2018. doi: 10.1038/s41586-018-0579-z.
D Yan, R Ahn, S. Leslie, W Liao. Clinical and Genetic Risk Factors Associated with Psoriatic Arthritis among Patients with Psoriasis. Dermatology and Therapy, 8, 593-604, 2018. doi: 10.1007/s13555-018-0266-x.
R Ahn, D. Vukcevic, A Motyers, D Ellinghaus, LC Tsoi, RP Nair, J Oksenberg, J Foerster, JT Elder, A Franke, E Jorgenson, S. Leslie, W Liao. Imputation of KIR Genes in over 80,000 Samples Reveals Previously Unknown Associations with Psoriasis. EXPERIMENTAL DERMATOLOGY, 27, 45 (1pp), 2018.
S Song, C Anderson, RT Good, S. Leslie, Y Wu, JG Oakeshott, C Robin. Population differentiation between Australian and Chinese Helicoverpa armigera occurs in distinct blocks on the Z-chromosome.. Bulletin of entomological research, 108, 817-830, 2018. doi: 10.1017/S0007485318000081.
Keren Abberton, Pei Tian, Andrew Elefanty, Ed Stanley, S. Leslie, Joanna Youngson, Mary Diviney, Rhonda Holdsworth, Karin Tiedemann, Melissa Little, Ngaire Elwood. Banked Cord Blood Is a Potential Source of Cells for Deriving Induced Pluripotent Stem Cell Lines Suitable for Cellular Therapy. Stem Cells Translational Medicine, 7, S13, 2018. doi: 10.1002/sctm.12363.
Paul A Lyons, James E Peters, Federico Alberici, James Liley, Richard MR Coulson, William Astle, Chiara Baldini, Francesco Bonatti, Maria C Cid, Heather Elding, Giacomo Emmi, Jörg Epplen, Loic Guillevin, David RW Jayne, Tao Jiang, Iva Gunnarsson, Peter Lamprecht, S. Leslie, Mark A Little, Davide Martorana, Frank Moosig, Thomas Neumann, Sophie Ohlsson, Stefanie Quickert, Giuseppe A Ramirez, Barbara Rewerska, Georg Schett, Renato A Sinico, Wojciech Szczeklik, Vladimir Tesar, D. Vukcevic, Benjamin Terrier, Richard A Watts, Augusto Vaglio, Julia U Holle, Chris Wallace, Kenneth GC Smith. Genetically distinct clinical subsets, and associations with asthma and eosinophil abundance, within Eosinophilic Granulomatosis with Polyangiitis. 2018. doi: 10.1101/491837.
Adrian Cortes, Calliope A Dendrou, Allan Motyer, Luke Jostins, D. Vukcevic, Alexander Dilthey, Peter Donnelly, S. Leslie, Lars Fugger, Gil McVean. Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank. Nature Genetics, 49, 1311-+, 2017. doi: 10.1038/ng.3926.
DJ Martino, S Ashley, J Koplin, J Ellis, R Saffery, SC Dharmage, L Gurrin, MC Matheson, B Kalb, I Marenholz, K Beyer, Y-A Lee, X Hong, X Wang, D. Vukcevic, A Motyer, S. Leslie, KJ Allen, MAR Ferreira. Genomewide association study of peanut allergy reproduces association with amino acid polymorphisms in HLA-DRB1. Clinical and Experimental Allergy, 47, 217-223, 2017. doi: 10.1111/cea.12863.
N Elwood, K Abberton, R Holdsworth, M Diviney, K Tiedemann, J Youngson, S. Leslie. Establishment of an Australian cord blood-derived IPSC haplobank for clinical use. Cytotherapy, 19, S53 (1pp), 2017.
C Bycroft, C Freeman, D Petkova, G Band, L Elliott, K Sharp, A. Motyer, D. Vukcevic, O Delaneau, A Cortes, S Welsh, G McVean, S. Leslie, P Donnelly, J Marchini. Genome-wide genetic data on ~500,000 UK Biobank participants. bioRxiv, 2017. doi: 10.1101/166298.
R Ahn, D. Vukcevic, A. Motyer, D Ellinghaus, LC Tsoi, RP Nair, C Palmer, J Oksenberg, J Foerster, JT Elder, A Franke, S. Leslie, W Liao. Large-scale imputation of killer cell immunoglobulin-like receptor copy number in psoriatic arthritis. BRITISH JOURNAL OF DERMATOLOGY, 177, E266-E267, 2017.
Adrian Cortes, Calliope A Dendrou, A. Motyer, Luke Jostins, D. Vukcevic, Alexander Dilthey, Peter Donnelly, S. Leslie, Lars Fugger, Gil McVean. Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank. 2017. doi: 10.1101/105122.
N Elwood, K Abberton, R Holdsworth, M Diviney, K Tiedemann, J Youngson, S. Leslie. Establishment of an Australian cord blood-derived iPSC haplobank for clinical use. Cytotherapy, 19, S75, 2017. doi: 10.1016/j.jcyt.2017.02.116.
A MOTYER, D. Vukcevic, A Dilthey, P Donnelly, G McVean, S. Leslie. Practical Use of Methods for Imputation of HLA Alleles from SNP Genotype Data. BioRxiv, 2016. doi: 10.1101/091009.
D. Vukcevic, James A Traherne, Sigrid Naess, Eva Ellinghaus, Yoichiro Kamatani, Alexander Dilthey, Mark Lathrop, Tom H Karlsen, Andre Franke, Miriam Moffatt, William Cookson, John Trowsdale, Gil McVean, Stephen Sawcer, S. Leslie, S Næss. Imputation of KIR Types from SNP Variation Data. American Journal of Human Genetics, 97, 593-607, 2015. doi: 10.1016/j.ajhg.2015.09.005.
S. Leslie, Bruce Winney, Garrett Hellenthal, Dan Davison, Abdelhamid Boumertit, Tammy Day, Katarzyna Hutnik, Ellen C Royrvik, Barry Cunliffe, Daniel J Lawson, Daniel Falush, Colin Freeman, Matti Pirinen, Simon Myers, Mark Robinson, Peter Donnelly, Walter Bodmer, Wellcome Trust Case Control Consortium 2, International Multiple Sclerosis Genetics Consortium. The fine-scale genetic structure of the British population. Nature, 519, 309-+, 2015. doi: 10.1038/nature14230.
Ian Wilmut, S. Leslie, Nicholas G Martin, Marc Peschanski, Mahendra Rao, Alan Trounson, David Turner, Shinya Yamanaka, Craig J Taylor. Development of a global network of induced pluripotent stem cell haplobanks. Regenerative Medicine, 10, 235-238, 2015. doi: 10.2217/RME.15.1.
Philippe Goyette, Gabrielle Boucher, Dermot Mallon, Eva Ellinghaust, Luke Jostins, Hailiang Huang, Stephan Ripke, Elena S Gusareva, Vito Annese, Stephen L Hauser, Jorge R Oksenberg, Ingo Thomsent, S. Leslie, Mark J Daly, Kristel Van Steen, Richard H Duerr, Jeffrey C Barrett, Dermot PB McGovern, L Philip Schumm, James A Traherne, Mary N Carrington, Vasilis Kosmoliaptsis, Tom H Karsen, Andre Franke, John D Rioux, E Ellinghaus, I Thomsen, TH Karlsen, C Abraham, JP Achkar, T Ahmad, L Amininejad, AN Ananthakrishnan, V Andersen, CA Anderson, JM Andrews, G Aumais, L Baidoo, RN Baldassano, T Balschun, PA Bampton, M Barclay, TM Bayless, J Bethge, JC Bis, A Bitton, S Brand, SR Brant, C Buning, A Chew, JH Cho, I Cleynen, A Cohain, A Croft, S Danese, D De Jong, M De Vos, G Denapiene, LA Denson, KL Devaney, O Dewit, M Dubinsky, C Edwards, J Essers, LR Ferguson, EA Festen, P Fleshner, T Florin, D Franchimont, K Fransen, R Gearry, M Georges, C Gieger, J Glas, International Inflammatory Bowel Disease Genetics Consortium, A. High-density mapping of the MHC identifies a shared role for HLA-DRB1(star)01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis. Nature Genetics, 47, 172-179, 2015. doi: 10.1038/ng.3176.
Loukas Moutsianas, Luke Jostins, Ashley H Beecham, Alexander T Dilthey, Dionysia K Xifara, Maria Ban, Tejas S Shah, Nikolaos A Patsopoulos, Lars Alfredsson, Carl A Anderson, Katherine E Attfield, Sergio E Baranzini, Jeffrey Barrett, Thomas MC Binder, David Booth, Dorothea Buck, Elisabeth G Celius, Chris Cotsapas, Calliope A Dendrou, Peter Donnelly, Benedicte Dubois, Bertrand Fontaine, Lars Fugger, An Goris, Pierre-Antoine Gourraud, Christiane Graetz, Bernhard Hemmer, Jan Hillert, Ingrid Kockum, S. Leslie, Christina M Lill, Filippo Martinelli-Boneschi, Jorge R Oksenberg, Tomas Olsson, Annette Oturai, Janna Saarela, Helle Bach Sondergaard, Anne Spurkland, Bruce Taylor, Juliane Winkelmann, Frauke Zipp, Jonathan L Haines, Margaret A Pericak-Vance, Chris CA Spencer, Graeme Stewart, David A Hafler, Adrian J Ivinson, Hanne F Harbo, Stephen L Hauser, Philip L De Jager, Alastair Compston, Jacob L McCauley, Stephen Sawcer, Gil McVean, HB SØndergaard, J L Haines, International IBD Genetics Consortium (IIBDGC), Helle B. Class II HLA interactions modulate genetic risk for multiple sclerosis. Nature Genetics, 47, 1107-+, 2015. doi: 10.1038/ng.3395.
V Damotte, L Guillot-Noel, NA Patsopoulos, L Madireddy, M El Behi, Maria Ban, Sergio Baranzini, Lisa Barcellos, Gary Beecham, Luisa Bernardinelli, David Booth, Steffan Bos, Dorothea Buck, William Bush, Manuel Comabella, Alastair Compston, Chris Cotsapas, Isabelle Cournu-Rebeix, Bruce Cree, Mark Daly, M. Davis, Paul de Bakker, Philip L De Jager, Benedicte Dubois, Federica Esposito, Bertrand Fontaine, An Goris, Pierre-Antoine Gourraud, Todd Green, Elisabeth Gulowsen Celius, Athena Hadjixenofontos, David Hafler, Jonathan Haines, Hanne F Flinstad, Stephen Hauser, Clive Hawkins, Bernhard Hemmer, Jan Hillert, Rogier Hintzen, Dana Horáková, Adrian J Ivinson, Anu Kemppinen, Jun-ichi Kira, Ingrid Kockum, Robin Lincoln, Roland Martin, Filippo Martinelli Boneschi, Jacob L McCauley, Inger-Lise Mero, Jorge Oksenberg, Tomas Olsson, Annette Oturai, Aarno Palotie, Margaret Pericak-Vance, John Rioux, Janna Saarela, Stephen Sawcer, Nathalie Schnetz-Boutaud, Finn Sellebjerg, Helle Soendergaard, Per Soelberg Sorensen, Anne Spu. A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility. Genes and Immunity, 15, 126-132, 2014. doi: 10.1038/gene.2013.70.
M. Turner, S. Leslie, NG Martin, M Peschanski, M Rao, C. Taylor, A Trounson, S Yamanaka, I Wilmut. Toward the Development of a Global Induced Pluripotent Stem Cell Library. Cell Stem Cell, 13, 382-384, 2013. doi: 10.1016/j.stem.2013.08.003.
Alexander Dilthey, S. Leslie, Loukas Moutsianas, Judong Shen, Charles Cox, Matthew R Nelson, Gil McVean. Multi-Population Classical HLA Type Imputation. PLoS Computational Biology, 9, e1002877 (13pp), 2013. doi: 10.1371/journal.pcbi.1002877.
Benjamin P Fairfax, Seiko Makino, Jayachandran Radhakrishnan, Katharine Plant, S. Leslie, Alexander Dilthey, Peter Ellis, Cordelia Langford, Fredrik O Vannberg, Julian C Knight. Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles. Nature Genetics, 44, 502-+, 2012. doi: 10.1038/ng.2205.
Bruce Winney, Abdelhamid Boumertit, Tammy Day, Dan Davison, Chikodi Echeta, Irina Evseeva, Katarzyna Hutnik, S. Leslie, Kristin Nicodemus, Ellen C Royrvik, Susan Tonks, 1631, James Cheshire, Paul Longley, Pablo Mateos, Alexandra Groom, Caroline Relton, D Tim Bishop, Kathryn Black, Emma Northwood, Louise Parkinson, Timothy M Frayling, Anna Steele, Julian R Sampson, T. King, Ron Dixon, Derek Middleton, Barbara Jennings, R. Bowden, Peter Donnelly, Walter Bodmer. People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population. European Journal of Human Genetics, 20, 203-210, 2012. doi: 10.1038/ejhg.2011.127.
MMA Fernando, J Freudenberg, A. Lee, DL Morris, L Boteva, B Rhodes, MF Gonzalez-Escribano, MA Lopez-Nevot, SV Navarra, PK Gregersen, J Martin, TJ Vyse, JD Rioux, P Goyette, L Hammarström, T Green, PL De Jager, S Foisy, J. Wang, PIW De Bakker, S. Leslie, G McVean, L Padyukov, L Alfredsson, V Annese, DA Hafler, Q Pan-Hammarström, R Matell, SJ Sawcer, AD Compston, BAC Cree, DB Mirel, MJ Daly, TW Behrens, L Klareskog, JR Oksenberg, SL Hauser, IMAGEN. Transancestral mapping of the MHC region in systemic lupus erythematosus identifies new independent and interacting loci at MSH5, HLA-DPB1 and HLA-G. Annals of the Rheumatic Diseases, 71, 777-784, 2012. doi: 10.1136/annrheumdis-2011-200808.
Alexander T Dilthey, S. Leslie, Judong Shen, Loukas Moutsianas, Matthew R Nelson, Gilean McVean. CLASSICAL HLA TYPE IMPUTATION FOR MULTI-POPULATION STUDIES. TISSUE ANTIGENS, 79, 418-419, 2012.
Loukas Moutsianas, Victor Enciso-Mora, Y. Ma, S. Leslie, Alexander Dilthey, Peter Broderick, Amy Sherborne, Rosie Cooke, Alan Ashworth, Anthony J Swerdlow, Gilean McVean, Richard S Houlston. Multiple Hodgkin lymphoma-associated loci within the HLA region at chromosome 6p21.3. Blood, 118, 670-674, 2011. doi: 10.1182/blood-2011-03-339630.
Alexander T Dilthey, Loukas Moutsianas, S. Leslie, Gil McVean. HLA*IMP-an integrated framework for imputing classical HLA alleles from SNP genotypes. Bioinformatics, 27, 968-972, 2011. doi: 10.1093/bioinformatics/btr061.
Fay J Hosking, S. Leslie, Alexander Dilthey, Loukas Moutsianas, Y Wang, Sara E Dobbins, Elli Papaemmanuil, Eamonn Sheridan, Sally E Kinsey, Tracy Lightfoot, Eve Roman, Julie AE Irving, James M Allan, Malcolm Taylor, Mel Greaves, Gilean McVean, Richard S Houlston. MHC variation and risk of childhood B-cell precursor acute lymphoblastic leukemia. Blood, 117, 1633-1640, 2011. doi: 10.1182/blood-2010-08-301598.
D. Evans, Chris CA Spencer, Jennifer J Pointon, Zhan Su, D. Harvey , Grazyna Kochan, Udo Opperman, Alexander Dilthey, Matti Pirinen, Millicent A Stone, Louise Appleton, Loukas Moutsianis, S. Leslie, Tom Wordsworth, Tony J Kenna, Tugce Karaderi, Gethin P Thomas, Michael M Ward, Michael H Weisman, Claire Farrar, Linda A Bradbury, Patrick Danoy, Robert D Inman, Walter Maksymowych, Dafna Gladman, Proton Rahman, Ann Morgan, Helena Marzo-Ortega, Paul Bowness, Karl Gaffney, JS Hill Gaston, Malcolm Smith, Jacome Bruges-Armas, Ana-Rita Couto, Rosa Sorrentino, Fabiana Paladini, Manuel A Ferreira, Huji Xu, Y. Liu, Lei Jiang, Carlos Lopez-Larrea, Roberto Diaz-Pena, Antonio Lopez-Vazquez, Tetyana Zayats, Gavin Band, Celine Bellenguez, Hannah Blackburn, Jenefer M Blackwell, Elvira Bramon, Suzannah J Bumpstead, Juan P Casas, Aiden Corvin, Nicholas Craddock, Panos Deloukas, Serge Dronov, Audrey Duncanson, Sarah Edkins, Colin Freeman, Matthew Gillman, Emma Gray, Rhian Gwilliam, Naomi Hammond, Sarah E Hunt, Janusz Jankowski, A. Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nature Genetics, 43, 761-U67, 2011. doi: 10.1038/ng.873.
MI Inouye, David M Altshuler, Richard A Gibbs, Leena Peltonen, Emmanouil Dermitzakis, Stephen F Schaffner, Fuli Yu, Penelope E Bonnen, Paul IW de Bakker, Panos Deloukas, Stacey B Gabriel, Rhian Gwilliam, Sarah Hunt, Xiaoming Jia, Aarno Palotie, Melissa Parkin, Pamela Whittaker, Kyle Chang, Alicia Hawes, Lora R Lewis, Yanru Ren, David Wheeler, Donna Marie Muzny, Chris Barnes, Katayoon Darvishi, Matthew Hurles, Joshua M Korn, Kati Kristiansson, C. Lee, Steven A McCarroll, James Nemesh, Alon Keinan, Stephen B Montgomery, Samuela Pollack, Alkes L Price, Nicole Soranzo, Claudia Gonzaga-Jauregui, Verneri Anttila, Wendy Brodeur, Mark J Daly, S. Leslie, Gil McVean, Loukas Moutsianas, Huy Nguyen, Q. Zhang, Mohammed JR Ghori, Ralph McGinnis, William McLaren, Fumihiko Takeuchi, Sharon R Grossman, Ilya Shlyakhter, Elizabeth B Hostetter, Pardis C Sabeti, Clement A Adebamowo, Morris W Foster, Deborah R Gordon, Julio Licinio, Maria Cristina Manca, Patricia A Marshall, Ichiro Matsuda, Duncan Ngare, Vivian Ota Wang, Deepa Red. Integrating common and rare genetic variation in diverse human populations. Nature, 467, 52-58, 2010. doi: 10.1038/nature09298.
A Strange, F Capon, CCA Spencer, J Knight, ME Weale, MH Allen, A Barton, G Band, C Bellenguez, JGM Bergboer, JM BlackweL, E Bramon, SJ Bumpstead, JP Casas, MJ Cork, A Corvin, P Deloukas, A Dilthey, A Duncanson, S Edkins, X EstiviL, O Fitzgerald, C FrEman, E Giardina, E Gray, A Hofer, U Hüffmeier, SE Hunt, AD Irvine, J Jankowski, B Kirby, C Langford, J Lascorz, J Leman, S. Leslie, L MaLbris, HS Markus, CG Mathew, WHI McLean, R McManus, R MöSner, L Moutsianas, AT Naluai, FO Nestle, G NoveLi, A Onoufriadis, CNA Palmer, C Perricone, M Pirinen, R Plomin, SC PoTer, RM Pujol, A Rautanen, E Riveira-Munoz, AW Ryan, W Salmhofer, L SamuelSon, SJ Sawcer, J Schalkwijk, CH Smith, M Ståhle, Z Su, R Tazi-Ahnini, H Traupe, AC Viswanathan, RB Warren, W Weger, K Wolk, N WOd, J Worthington, HS Young, PLJM Zeeuwen, A Hayday, AD Burden, CEM Griffiths, J Kere, A Reis, G McVean, D. Evans, MA Brown, JN Barker, L Peltonen, P Donely, RC Trembath, Genetic Analysis of Psoriasis Consortium & the Wellcome Trust Case Control Consortium . A genome-wide asociation study identifies new psoriasis susceptibility loci and an interaction betwEn HLA-C and ERAP1. Nature Genetics, 42, 985-990, 2010. doi: 10.1038/ng.694.
JD Rioux, P Goyette, TJ Vyse, L Hammarström, MMA Fernando, T Green, PL De Jager, S Foisy, J. Wang, PIW De Bakker, S. Leslie, G McVean, L Padyukov, L Alfredsson, V Annese, DA Hafler, Q Pan-Hammarström, R Matell, SJ Sawcer, AD Compston, BAC Cree, DB Mirel, MJ Daly, TW Behrens, L Klareskog, PK Gregersen, JR Oksenberg, SL Hauser, International MHC and Autoimmunity Genetics Network, L Hammarstrom, Q Pan-Hammarstrom. Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases. Proceedings of the National Academy of Sciences of the United States of America, 106, 18680-18685, 2009. doi: 10.1073/pnas.0909307106.
S. Leslie, P Donnelly, G McVean. A Statistical Method for Predicting Classical HLA Alleles from SNP Data. American Journal of Human Genetics, 82, 48-56, 2008. doi: 10.1016/j.ajhg.2007.09.001.